Welcome to the home of network biology at Washington University in St. Louis
Our Mission: Model, predict and design functions of biological systems that result from integration of signals and responses of biomolecular and cellular networks.
Fall 2014 CBSE seminar series:
Noon (12 PM)
Jan 20th: Doug Barrick, Johns Hopkins University
Hughes TB, Miller GP, and Swamidass SJ (2015)
Site of Reactivity Models Predict Molecular Reactivity of Diverse Chemicals with Glutathione. Chem. Res. Toxicol., In press
Holehouse AS, Garai K, Lyle N, Vitalis A, Pappu RV (2015)
Quantitative assessments of the distinct contributions of polypeptide backbone amides versus sidechain groups to chain expansion via chemical denaturation. JACS, 137: 2984-2995
Zaretzki J, Browning M, Hughes TB and Swamidass SJ (2015)
Extending P450 Site-of-Metabolism Models with Region-Resolution Data. Bioinformatics, In press
Matlock MK, Holehouse AS, Naegle KM (2015)
ProteomeScout: a repository and analysis resource for post-translational modifications and proteins. Nucleic Acids Research, 43 (D1) , D521-D530
Ruff KM, Khan SJ, Pappu RV (2014)
A coarse-grained model for polyglutamine aggregation modulated by amphipathic flanking sequences. Biophysical Journal, Vol. 107 no. 5 pp. 1226-1235.
Xu Q, Sawatzky A, Roessl E, Anastasio MA, Schirra CO (2014)
Sparsity-regularized image reconstruction of decomposed K-edge data in spectral CT. Phys. Med. Biol., Vol. 21 no. 10 pp. N65-79
Reese TA, Wakeman BS, Choi HS, Hufford MM, Huang SC, Zhang X, Buck MD, Jezewski A, Kambal A, Liu CY, Goel G, Murray PJ, Xavier RJ, Kaplan MH, Renne R, Speck SH, Artyomov MN, Pearce EJ, Virgin HW (2014)
Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter. Science, Vol. 345 no. 6196 pp. 573-577.
Xu W, Edwards MR, Borek DM, Feagins AR, Mittal A, Alinger JB, Berry KN, Yen B, Hamilton J, Brett TJ, Pappu RV, Leung DW, Basler CF, Amarasinghe GK (2014)
Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1. Cell Host & Microbe, 16, pp. 187-200.
Predeus A, Gopalakrishnan S, Huang Y, Tung J, Feeney AJ, Oltz EM, Artyomov MN. (2014)
Chromatin Profiling Reveals Novel Enhancers in Immunoglobulin Heavy and Light Chain Loci. J Immunol , 1;129(3) pp. 1064-1070
Cho Y, Sloutsky R, Naegle KM, Cavalli V. (2013)
Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration. Cell, 155 pp. 894 – 908
Sloutsky R, Jimenez N, Swamidass SJ, Naegle KM. (2013)
Accounting for noise when clustering biological data.
Brief. Bioinform. 14, pp 423 – 436